Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
USERS' SCORE
Moderately Good
Based on 29 Reviews
7.4
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Choline (from 630 mg Choline Bitartrate)
250 mg
45%
Inositol
250 mg
â€
Top Medical Research Studies
9
We investigated how inositol supplementation could counteract heart issues caused by lithium in mice. Our study involved four groups of mice to explore the varying effects of inositol. One group received lithium alone, another received lithium followed by inositol, a third group had both lithium and inositol from the start, and a control group had no treatment at all.
The results were promising. We found that inositol had a protective effect against the heart damage typically associated with lithium. Specifically, it helped improve heart function and reduced susceptibility to arrhythmias—irregular heartbeats. We also noted that inositol seemed to restore healthy levels of certain proteins crucial for heart health, helping to reduce cell enlargement and stress associated with hypertrophy.
Interestingly, the benefits of inositol were evident regardless of whether it was given alongside lithium or afterward as a treatment. These findings suggest that inositol could be a valuable addition to therapy for those facing lithium-induced cardiac issues, offering a potential pathway to better heart health.
The results were promising. We found that inositol had a protective effect against the heart damage typically associated with lithium. Specifically, it helped improve heart function and reduced susceptibility to arrhythmias—irregular heartbeats. We also noted that inositol seemed to restore healthy levels of certain proteins crucial for heart health, helping to reduce cell enlargement and stress associated with hypertrophy.
Interestingly, the benefits of inositol were evident regardless of whether it was given alongside lithium or afterward as a treatment. These findings suggest that inositol could be a valuable addition to therapy for those facing lithium-induced cardiac issues, offering a potential pathway to better heart health.
Read More
8
ITPP improves heart function in PH
We investigated the effects of myo-inositol trispyrophosphate (ITPP) on rats with pulmonary hypertension (PH), a condition that often leads to serious heart issues. To do this, we injected some rats with monocrotaline to induce PH and treated others with a placebo. For five weeks, we closely monitored their heart function using echocardiograms and other advanced techniques.
Our findings revealed that ITPP significantly reduced mortality linked to PH. While it didn't change the increasing resistance in the pulmonary vessels, ITPP importantly alleviated hypoxia within the right ventricle (RV), which is crucial for maintaining heart function. This reduction in RV hypoxia not only improved heart performance but also decreased stress on the heart’s structure.
Furthermore, we noticed that ITPP appeared to inhibit an increase in a specific protein associated with low oxygen levels, though it didn't affect the density of blood vessels in the RV. Overall, this suggests that enhancing oxygen delivery with ITPP could provide a crucial therapeutic avenue for improving heart health in patients suffering from pulmonary hypertension.
Our findings revealed that ITPP significantly reduced mortality linked to PH. While it didn't change the increasing resistance in the pulmonary vessels, ITPP importantly alleviated hypoxia within the right ventricle (RV), which is crucial for maintaining heart function. This reduction in RV hypoxia not only improved heart performance but also decreased stress on the heart’s structure.
Furthermore, we noticed that ITPP appeared to inhibit an increase in a specific protein associated with low oxygen levels, though it didn't affect the density of blood vessels in the RV. Overall, this suggests that enhancing oxygen delivery with ITPP could provide a crucial therapeutic avenue for improving heart health in patients suffering from pulmonary hypertension.
Read More
Most Useful Reviews
9
Fatty liver control
14 people found this helpful
I've used this product for 10 years after being diagnosed with fatty liver. Despite not changing my lifestyle, regular testing has shown normal liver function. Choline and inositol significantly help reduce fatty deposits, promoting liver health.
Read More
7.5
Enhanced performance
57 people found this helpful
I have been taking NOW Foods Choline and Inositol for a month, and I feel invigorated with improved performance. My energy and concentration have noticeably increased, helping with mental stress. My liver health has improved, cholesterol levels are better, and chronic fatigue has lessened significantly. Overall, this supplement has improved my well-being, but I recommend consulting a doctor before use.
Read More
0
Nervousness experienced
42 people found this helpful
After taking one capsule post-meal, the effects were aggressive and nervous for both adults and children. Choline increases nerve fiber conductivity, causing excessive brain excitation; I certainly do not recommend it for children or middle-aged individuals.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
- All Researches
9
We investigated how inositol supplementation could counteract heart issues caused by lithium in mice. Our study involved four groups of mice to explore the varying effects of inositol. One group received lithium alone, another received lithium followed by inositol, a third group had both lithium and inositol from the start, and a control group had no treatment at all.
The results were promising. We found that inositol had a protective effect against the heart damage typically associated with lithium. Specifically, it helped improve heart function and reduced susceptibility to arrhythmias—irregular heartbeats. We also noted that inositol seemed to restore healthy levels of certain proteins crucial for heart health, helping to reduce cell enlargement and stress associated with hypertrophy.
Interestingly, the benefits of inositol were evident regardless of whether it was given alongside lithium or afterward as a treatment. These findings suggest that inositol could be a valuable addition to therapy for those facing lithium-induced cardiac issues, offering a potential pathway to better heart health.
The results were promising. We found that inositol had a protective effect against the heart damage typically associated with lithium. Specifically, it helped improve heart function and reduced susceptibility to arrhythmias—irregular heartbeats. We also noted that inositol seemed to restore healthy levels of certain proteins crucial for heart health, helping to reduce cell enlargement and stress associated with hypertrophy.
Interestingly, the benefits of inositol were evident regardless of whether it was given alongside lithium or afterward as a treatment. These findings suggest that inositol could be a valuable addition to therapy for those facing lithium-induced cardiac issues, offering a potential pathway to better heart health.
Read More
8
ITPP improves heart function in PH
We investigated the effects of myo-inositol trispyrophosphate (ITPP) on rats with pulmonary hypertension (PH), a condition that often leads to serious heart issues. To do this, we injected some rats with monocrotaline to induce PH and treated others with a placebo. For five weeks, we closely monitored their heart function using echocardiograms and other advanced techniques.
Our findings revealed that ITPP significantly reduced mortality linked to PH. While it didn't change the increasing resistance in the pulmonary vessels, ITPP importantly alleviated hypoxia within the right ventricle (RV), which is crucial for maintaining heart function. This reduction in RV hypoxia not only improved heart performance but also decreased stress on the heart’s structure.
Furthermore, we noticed that ITPP appeared to inhibit an increase in a specific protein associated with low oxygen levels, though it didn't affect the density of blood vessels in the RV. Overall, this suggests that enhancing oxygen delivery with ITPP could provide a crucial therapeutic avenue for improving heart health in patients suffering from pulmonary hypertension.
Our findings revealed that ITPP significantly reduced mortality linked to PH. While it didn't change the increasing resistance in the pulmonary vessels, ITPP importantly alleviated hypoxia within the right ventricle (RV), which is crucial for maintaining heart function. This reduction in RV hypoxia not only improved heart performance but also decreased stress on the heart’s structure.
Furthermore, we noticed that ITPP appeared to inhibit an increase in a specific protein associated with low oxygen levels, though it didn't affect the density of blood vessels in the RV. Overall, this suggests that enhancing oxygen delivery with ITPP could provide a crucial therapeutic avenue for improving heart health in patients suffering from pulmonary hypertension.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 29 Reviews
7.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Fatty liver control
14 people found this helpful
I've used this product for 10 years after being diagnosed with fatty liver. Despite not changing my lifestyle, regular testing has shown normal liver function. Choline and inositol significantly help reduce fatty deposits, promoting liver health.
Read More
7.5
Enhanced performance
57 people found this helpful
I have been taking NOW Foods Choline and Inositol for a month, and I feel invigorated with improved performance. My energy and concentration have noticeably increased, helping with mental stress. My liver health has improved, cholesterol levels are better, and chronic fatigue has lessened significantly. Overall, this supplement has improved my well-being, but I recommend consulting a doctor before use.
Read More
0
Nervousness experienced
42 people found this helpful
After taking one capsule post-meal, the effects were aggressive and nervous for both adults and children. Choline increases nerve fiber conductivity, causing excessive brain excitation; I certainly do not recommend it for children or middle-aged individuals.
Read More
7.5
Memory and cognition
39 people found this helpful
Choline aids in treating liver diseases, depression, and cognitive decline. It's also beneficial for pregnant women to prevent neural tube defects in infants. Meanwhile, inositol helps with several conditions including high cholesterol and depression. These supplements have a broad range of positive effects.
Read More
7.5
Cognitive function
23 people found this helpful
Choline and inositol, both B vitamins, support liver function and cholesterol metabolism. Choline enhances cognitive speed while inositol calms tension and lowers blood pressure. After three months of use, my cholesterol normalised, and I feel far more purposeful and active.
Read More
Frequently Asked Questions
7.5
Enhanced performance
57 people found this helpful
I have been taking NOW Foods Choline and Inositol for a month, and I feel invigorated with improved performance. My energy and concentration have noticeably increased, helping with mental stress. My liver health has improved, cholesterol levels are better, and chronic fatigue has lessened significantly. Overall, this supplement has improved my well-being, but I recommend consulting a doctor before use.
9
Improved wellbeing
1 people found this helpful
I have been taking the NOW Foods Choline and Inositol supplement for about a month. It invigorates and enhances performance, providing more energy and concentration. My cholesterol levels improved, and my sleep normalised. Overall, I find it effective for enhancing wellbeing and protecting against various diseases, including cardiovascular disease. I recommend consulting with a doctor before taking it, especially if on other medications.
7.5
Cognitive function
23 people found this helpful
Choline and inositol, both B vitamins, support liver function and cholesterol metabolism. Choline enhances cognitive speed while inositol calms tension and lowers blood pressure. After three months of use, my cholesterol normalised, and I feel far more purposeful and active.
9
Cognitive improvement
10 people found this helpful
Great product! I've bought this several times. I take one capsule daily after lunch, and it significantly enhances memory and cardiovascular functioning. The effect seems cumulative, especially when combined with exercise and a healthy lifestyle. I recommend trying this supplement; I experienced no side effects, only positives.
9
Fatty liver control
14 people found this helpful
I've used this product for 10 years after being diagnosed with fatty liver. Despite not changing my lifestyle, regular testing has shown normal liver function. Choline and inositol significantly help reduce fatty deposits, promoting liver health.
7.5
Heart muscle health
15 people found this helpful
Choline plays a critical role in lowering cholesterol levels, clearing blood vessels of plaques, and reducing homocysteine, hence mitigating the risk of cardiovascular disease. It strengthens the heart muscle and normalises heart rhythm, making it essential for heart health.
7.5
Health benefits
This supplement offers a good dosage of 250 mg of choline and inositol, beneficial for various issues, including cardiovascular disease, female health, liver detox, and cholesterol reduction. I take one to two tablets daily with meals.
7.5
Nootropic benefits
9 people found this helpful
Inositol complements choline by aiding cholesterol and fat metabolism. Choline is key for neurotransmitter production, essential for managing cardiovascular disease, memory, and liver protection. When combined with regular exercise, a daily dosage of about 1g is advisable. Inositol promotes relaxation and has properties beneficial for cardiovascular issues and nervous tissue restoration.
9
We investigated how inositol supplementation could counteract heart issues caused by lithium in mice. Our study involved four groups of mice to explore the varying effects of inositol. One group received lithium alone, another received lithium followed by inositol, a third group had both lithium and inositol from the start, and a control group had no treatment at all.
The results were promising. We found that inositol had a protective effect against the heart damage typically associated with lithium. Specifically, it helped improve heart function and reduced susceptibility to arrhythmias—irregular heartbeats. We also noted that inositol seemed to restore healthy levels of certain proteins crucial for heart health, helping to reduce cell enlargement and stress associated with hypertrophy.
Interestingly, the benefits of inositol were evident regardless of whether it was given alongside lithium or afterward as a treatment. These findings suggest that inositol could be a valuable addition to therapy for those facing lithium-induced cardiac issues, offering a potential pathway to better heart health.
The results were promising. We found that inositol had a protective effect against the heart damage typically associated with lithium. Specifically, it helped improve heart function and reduced susceptibility to arrhythmias—irregular heartbeats. We also noted that inositol seemed to restore healthy levels of certain proteins crucial for heart health, helping to reduce cell enlargement and stress associated with hypertrophy.
Interestingly, the benefits of inositol were evident regardless of whether it was given alongside lithium or afterward as a treatment. These findings suggest that inositol could be a valuable addition to therapy for those facing lithium-induced cardiac issues, offering a potential pathway to better heart health.
8
ITPP improves heart function in PH
We investigated the effects of myo-inositol trispyrophosphate (ITPP) on rats with pulmonary hypertension (PH), a condition that often leads to serious heart issues. To do this, we injected some rats with monocrotaline to induce PH and treated others with a placebo. For five weeks, we closely monitored their heart function using echocardiograms and other advanced techniques.
Our findings revealed that ITPP significantly reduced mortality linked to PH. While it didn't change the increasing resistance in the pulmonary vessels, ITPP importantly alleviated hypoxia within the right ventricle (RV), which is crucial for maintaining heart function. This reduction in RV hypoxia not only improved heart performance but also decreased stress on the heart’s structure.
Furthermore, we noticed that ITPP appeared to inhibit an increase in a specific protein associated with low oxygen levels, though it didn't affect the density of blood vessels in the RV. Overall, this suggests that enhancing oxygen delivery with ITPP could provide a crucial therapeutic avenue for improving heart health in patients suffering from pulmonary hypertension.
Our findings revealed that ITPP significantly reduced mortality linked to PH. While it didn't change the increasing resistance in the pulmonary vessels, ITPP importantly alleviated hypoxia within the right ventricle (RV), which is crucial for maintaining heart function. This reduction in RV hypoxia not only improved heart performance but also decreased stress on the heart’s structure.
Furthermore, we noticed that ITPP appeared to inhibit an increase in a specific protein associated with low oxygen levels, though it didn't affect the density of blood vessels in the RV. Overall, this suggests that enhancing oxygen delivery with ITPP could provide a crucial therapeutic avenue for improving heart health in patients suffering from pulmonary hypertension.
References
- L'Abbate S, Nicolini G, Forini F, Lepore E, Marchetti S, et al. Oral supplementation of inositols effectively recovered lithium-induced cardiac dysfunctions in mice. Biomed Pharmacother. 2024;178:117287. 10.1016/j.biopha.2024.117287
- Oknińska M, Paterek A, Grzanka M, Zajda K, Surzykiewicz M, et al. Myo-inositol trispyrophosphate prevents right ventricular failure and improves survival in monocrotaline-induced pulmonary hypertension in the rat. Br J Pharmacol. 2024;181:4050. 10.1111/bph.16482
